MURDER OF TUPAC SHAKUR

Hours before Shakur's shooting on the night of September 7, 1996, Anderson was involved in a fight with Shakur and his entourage at the MGM Grand Hotel in Las Vegas. In September, Las Vegas homicide Lt. Larry Spinosa told the media, "At this point, Orlando Anderson is not a suspect in the shooting of Tupac Shakur." Eventually in the investigation, Anderson was named a suspect along with his uncle. Stories circulated on the street that Anderson bragged about shooting the rapper, which he denied in an interview for VIBE magazine later.

Anderson was detained in Compton a month after the shooting with 21 other alleged gang members. Anderson was not charged. However, the raid was only tangentially connected to the Tupac shooting as Compton police said they were investigating local shootings and not the one in Las Vegas.

The Las Vegas police discounted Anderson as a suspect, according to a Los Angeles Times article, because the fight, in which Shakur was involved in assaulting Orlando Anderson in the Las Vegas MGM lobby, had happened just hours before the shooting. They failed to follow up with a member of Shakur's entourage who witnessed the shooting and told Vegas police he could identify one or more of the assailants—the witness, rapper Yaki Kadafi, was killed two months later—and they also failed to follow up on a lead from a witness who had spotted a white Cadillac similar to the car from which the fatal shots were fired and in which the shooters escaped.

A year later, Afeni Shakur, Tupac's mother, filed a wrongful death lawsuit against Anderson in response to a lawsuit Anderson filed against Death Row Records CEO Suge Knight, Death Row associates, and Tupac's estate. Anderson's lawsuit sought damages for injuries resulting from the scuffle the evening of Tupac's murder, for emotional and physical pain. Afeni Shakur's lawsuit was filed just four days after Anderson's. The Associated Press reported in 2000 that Shakur's estate and Anderson's estate settled the competing lawsuits just hours before the death of Orlando Anderson. Anderson's lawyer claimed the settlement would have netted Anderson $78,000. In September 1997, Anderson told the Los Angeles Times he was a fan of Tupac Shakur and his music, and denied having anything to do with the murder.

On September 29, 2023, Davis was taken into custody by Las Vegas Metropolitan Police in connection with the murder. A house owned by his wife in nearby Henderson, Nevada, had been raided by police on July 17, 2023. Police documents stated that they were looking for items "concerning the murder of Tupac Shakur" in the raid.